Lesion Formation With Pulsed Field Versus Cryobaloon Ablation as Assessed by Cardiac Magnetic Resoncance
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This randomised study will compare pulsed field ablation and cryoballoon ablation with respect to ablation lesion quality as assessed by late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) at 3 months post-ablation. Patients scheduled for first-time AF ablation will be randomised in a 2:1 fashion to receive PVI-only, either by pulsed field ablation (Farapulse Pulsed Field Ablation System, Boston Scientific) or cryoballoon ablation (Medtronic Cryoballoon Ablation System).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients scheduled for first-time atrial fibrillation catheter ablation
Locations
Other Locations
Spain
Hospital Clinic, University of Barcelona
RECRUITING
Barcelona
Time Frame
Start Date: 2023-11-01
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 104
Treatments
Experimental: Pulsed Field Ablation
Pulmonary vein isolation using the Farapulse Pulsed Field Ablation System (Boston Scientific)
Active_comparator: Cryoballoon Ablation
Pulmonary vein isolation using the Medtronic Cryoballoon Ablation System
Related Therapeutic Areas
Sponsors
Leads: Hospital Clinic of Barcelona